Which of the following best explains the working of a gene drive?

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A gene drive is a genetic engineering technology that uses CRISPR to ensure that a specific genetic modification is inherited by a high proportion of offspring, effectively "driving" that gene through a population. This is achieved by causing the editing of a gene on one chromosome in such a way that it can copy itself onto the homologous chromosome during reproduction. As a result, the modified trait becomes more prevalent in subsequent generations, thus influencing the population dynamics.

This process contrasts with traditional inheritance, where a gene has only a 50% chance of being passed on to the next generation. The utilization of CRISPR technology allows for precise edits to DNA, which makes it a powerful tool in gene drive applications. The intention behind gene drives often relates to controlling pest populations, eradicating diseases, or modifying traits in specific organisms to promote environmental and agricultural benefits.

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